Protein Details: Probable aquaporin SIP1-2

Protein ID

ICDB_Pro_1493

Protein Name

Probable aquaporin SIP1-2

Gene Name

SIP1-2; At5g18290; F20L16_10; MRG7.25

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

243 amino acids

AlphaFoldDB

AF-Q9FK43-F1-model_v4.pdb

Function

Water channel required to facilitate the transport of water across cell membrane.

Sequence

MSAVKSALGDMVITFLWVILSATFGIQTAAIVSAVGFHGITWAPLVISTLVVFVSISIFTVIGNVLGGASFNPCGNAAFYTAGVSSDSLFSLAIRSPAQAIGAAGGAITIMEMIPEKYKTRIGGKPSLQFGAHNGAISEVVLSFSVTFLVLLIILRGPRKLLAKTFLLALATVSVFVVGSKFTRPFMNPAIAFGWAYIYKSHNTWDHFYVYWISSYTGAILSAMLFRIIFPAPPLVQKKQKKA

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed in roots and above ground. Expressed in elongating regions of the root tips; cotyledons; minor veins and hydathode cells of the rosette leaves. Weakly expressed in vascular tissues of the flower petals; filaments of stamens; upper part of the styles and receptacles of the siliques. Weakly expressed in vascular tissues of the flower petals; filaments of stamens; upper part of the styles and receptacles of the siliques. Weakly expressed in vascular tissues of the flower petals; filaments of stamens; upper part of the styles and receptacles of the siliques.

DOI ID

10.1093/dnares/5.3.203; 10.1111/tpj.13415; 10.1126/science.1071006; 10.1126/science.1088305; 10.1186/gb-2001-3-1-research0001; 10.1016/j.febslet.2005.09.076

RefSeq

NP_001190329.1; NP_197330.1